But the research also suggests that the same effect is
not found in those who eat lots of fruit.
"It's a modest effect," said Martha Clare
Morris, associate professor at Rush University Medical
Center in Chicago, and lead author of the study.
"People who consumed two or more vegetables a day had
a 35 to 40 percent decrease in the decline in thinking
ability over six years. That's the equivalent of being
five years younger in age."
The study results are published in the Oct. 24 issue of
the journal Neurology.
Morris' team studied 3,718 research participants 65 or
older who live in the south side of Chicago. Sixty-two
percent were black, 38 percent were non-Hispanic white,
and 62 percent were female.
"We used a complete food questionnaire of 139
different food items," Morris said. "We asked
about their usual intake and assessed the frequency of
intake." During the six-year study, the participants
received at least two cognitive tests that measured their
memory and thinking speed.
"By far, the association with a slower rate of
decline was found in the group that ate high amounts of
green, leafy vegetables," Morris said. Such foods
included lettuce and tossed salad, spinach, kale and
collards.
The study also found that the slowdown in cognitive
decline was greatest in the oldest people who ate at least
two more vegetable servings a day.
Because the cognitive tests measured overall thinking
ability, the benefits of eating vegetables may translate
into an easier time with such everyday tasks as
remembering phone numbers and names and balancing
checkbooks, Morris said.
Morris suspects that vegetables may help protect memory
and thinking speed because they contain high amounts of
vitamin E, an antioxidant that can help reduce the damage
caused by free radicals, unstable oxygen molecules
generated by normal metabolism that can damage neurons in
the brain and contribute to dementia.
"We had found in previous studies that vitamin E
in food protected against cognitive decline and the
development of Alzheimer's disease," she said.
Her previous research also had shown that consumption
of healthy fats, such as the polyunsaturated and
monounsaturated fats found in foods such as olive oil,
were similarly protective.
"When we eat vegetables, we tend to put the good
fats on them, such as an oil-based salad dressing on
salads, healthy-fat mayonnaise on cole slaw, and
healthy-fat margarine on vegetables," Morris said.
"Such fats help us to absorb the vitamin E, and
perhaps are also beneficial to the brain. So that's one
plausible explanation of why vegetables are good for
you."
Morris' study also found that high consumption of fruit
had no effect on thinking ability. A similar large-scale
study, the Nurses' Health Study, also found that high
vegetable consumption, but not high fruit consumption, was
associated with a slower rate of cognitive decline.
One of the most common antioxidants found in fruit,
vitamin C, has not been consistently shown to protect the
brain, Morris said. Most of her study participants
consumed fruit such as oranges, grapefruits, apples and
bananas, which are high in vitamin C.
It's possible that some fruit may contain
compounds that counteract antioxidants. Further studies
are needed to determine whether fruit is brain-protective,
she said.
As for eating vegetables, Morris said it's too soon to
say for sure that they actually preserve the brain from
age-related decline. "But it's encouraging to see
that it appears to slow the rate of decline," she
said. "We know that eating vegetables is important
for chronic diseases. So this might be one more reason why
you should eat your vegetables."
In her next study of the same group of Chicago
residents, Morris hopes to examine whether high vegetable
consumption helps protect against Alzheimer's disease.
Results are expected in the next year, she said.
Dallas Anderson is program director for epidemiologic
studies of Alzheimer's disease at the National Institute
on Aging. "It may be premature to discount the role
of fruit consumption in maintaining cognitive
health," he said, citing recent research showing that
weekly consumption of three or more servings of fruit and
vegetable juices was associated with a reduced risk of
Alzheimer's.
"Further research will be needed to take account
of how the fruit is prepared, as peeling may greatly
reduce the amounts of antioxidants available,"
Anderson said.
"I anticipate that further research will refine
what we know about the relationship between fruit and
vegetable consumption and cognitive function, helping to
determine more definitively the types and amounts of foods
that may preserve cognition," he added.